JL: Comment 1/30/99: Although O. T. Avery had a cardinal role of intellectual influence on my life, I had almost no personal contact with him. Supra is the only item of correspondence; and I did call on him ca. 1946-47 -- perhaps there will be some record of that in my correspondence with Harriett Taylor, who was working with him at the time. The literature reference is: Goebel WF; Avery OT Chemo-immunological studies on conjugated carbohydrate-proteins. 1. The synthesis of p-aminophenol beta-glucoside, p-aminophenol beta-galactoside, and their coupling with serum globulin. Journal of Experimental Medicine 50: 521-531 1929 -------------- This has to do with my quest for chromogenic substrates to be used in the assay of B-galactosidase, in particular for the nitrophenyl galactoside. This was an intermediate in the synthesis of the aminophenyl compounds used in the Avery/Goebel and Landsteiner immunochemical studies. Somewhat later, I elicited the interest of Karl Paul Link at Wisconsin, and his student Martin Seidman worked out an excellent synthesis. See P-21.