Thank you for your perspectives on the transforming factor. On rereading Avery, Macleod and McCarty, I felt Del[?] Mirsky's
doubts were malicious, since they had proved that p[ . . . ]dylic enzymes, RNAase, and succharans[?] left the transforming
principle intact, wheeras [sic] DNAase destroyed it. Mirsky had [ . . . ]ed with DNA for years without realising [sic] its
import which I regard as the motive for his doubts. Jim Watson had none when he joined us in 1959, and his convictions were
reinforced on hearing H[ . . . ]ey and Chen at Cold Spring Harbor in the following year. Did the doubters whom you quote
understand enzyme biochemistry? Had they read the paper?