In this mildly controversial article, Dochez and Avery presented their theory of antiblastic immunity--the resistance to pneumococci
as a result of the inhibition of particular pneumococcal enzymes by the serum from an infected person or animal--that promised
to shed considerable light on the mechanisms by which parasitic bacteria establish themselves in animal tissue. Subsequent
research conducted by others at the Rockefeller Institute determined that although antipneumococcal serum could retard the
growth of pneumococci, it was not due to inhibition of enzymatic activity but the result of agglutination, which had few practical
applications, effectively disproving Avery and Dochez's theory of antiblastic immunity.
Item is a photocopy.
Number of Image Pages:
8 (654,008 Bytes)
1916-01 (January 1916)
Dochez, A. R.
Avery, Oswald T.
Periodical: Dochez, A. R., and Oswald T. Avery. "Antiblastic Immunity." Journal of Experimental Medicine 23, 1 (January 1916):
61-68. Article. 8 Images.
Rockefeller University Press
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From Physician to Researcher: Early Laboratory Career and World War I, 1904-1919