The Soluble Specific Substance of Pneumococcus: Second Paper
Avery's research on the specific soluble substance, or SSS, was an attempt to identify the substance that was responsible
for the specific immunological reactions produced in pneumonia patients. Here, Avery and Heidelberger elaborated on their
first paper (published in 1923) by indicating that they had improved the technique for the concentration and purification
of SSS, and reported that distinct differences existed between the SSS of type-II and type-III pneumococci. The collaboration
between Avery and Heidelberger initiated a line of research that yielded two articles, and, after Heidelberger left for Mount
Sinai Hospital in 1924, several by Avery with Walther Goebel and F. H. Babers in the late 1920s.
Item is a photocopy.
Number of Image Pages:
16 (1,448,670 Bytes)
1924-08 (August 1924)
Avery, Oswald T.
Periodical: Heidelberger, Michael, and Oswald T. Avery. "The Soluble Specific Substance of Pneumococcus: Second Paper." Journal
of Experimental Medicine 40, 3 (August 1924): 301-316. Article. 16 Images.
Rockefeller University Press
Reproduced from the Journal of Experimental Medicine, 1924, 40, 301-316, by copyright permission of the Rockefeller University
The "Sugar-Coated Microbe" and the Search for a Cure for Pneumonia, 1919-1929
The Making of an Immunologist: Heidelberger's Years at the Rockefeller Institute, 1912-1927
The Elaboration of Specific Soluble Substance by Pneumococcus During Growth [2-3 May 1917]
The Soluble Specific Substance of Pneumococcus (June 1923)
Immunologic Relationships of Cell Constituents of Pneumococcus (June 1923)