Original Repository: Stanford University Libraries. Department of Special Collections and University Archives. Paul Berg Papers
Reproduced with permission of Paul Berg.
Medical Subject Headings (MeSH):
Molecular Biology and a Changing Academic Landscape, 1980-present
Letter from Marianne Grunberg-Manago to Paul Berg (May 10, 1979)
Letter from Paul Berg to Marianne Grunberg-Manago (July 5, 1979)
June 8, 1979
I'm sorry for the delay in sending you the information about translation of the globin sequence in SV40-beta-globin cDNA
recombinants. We have a few experiments in progress, hopefully to be finished in the next few weeks, that would provide a
better understanding than I could give you in Koln. We should have finished the determination on an experiment we have collaborated
OR with Charles Weissmann. He constructed rabbit beta-globin cDNA "mutations" in which various portions of the 5'-sequence
of the beta-globin cDNA have been deleted (including one with the AUG gene) and we have inserted these into SV40 to see how
much of the sequence in front of the beta-globin AUG is needed for expression. In the meantime I enclose a reprint of our
Jan. Nature paper. I'll write you as soon as the date is available which as I say is imminent.
It was nice to see you again if only briefly. I hope we'll meet soon, hopefully if I can stop in Paris at the end of September.