The Transmission of Meperidine across the Human Placenta
Much of Apgar's research during the early 1950s focused on the effects of maternal anesthesia on the newborn child; she
and other investigators asked whether anesthetic agents crossed the placenta from mother to fetus, and if so, whether the
drugs endangered the baby. In this case, they found that meperidine (Demerol) did cross the placental barrier, but did not
depress the respiration of the newborn.
Item is a photocopy.
Number of Image Pages:
3 (188,468 Bytes)
1952-12 (December 1952)
Burns, J. J.
Brodie, Bernard B.
Papper, E. M.
Periodical: Apgar, Virginia, J. J. Burns, Bernard B. Brodie, and E. M. Papper. "The Transmission of Meperidine across the Human Placenta."
American Journal of Obstetrics and Gynecology 64, 6 (December 1952): 1368-1370. Article. 3 Images.
[C. V. Mosby Company]
Reprinted from American Journal of Obstetrics and Gynecology, 64, Apgar, Virginia, J. J. Burns, Bernard B. Brodie, and E.
M. Papper, "The Transmission of Meperidine across the Human Placenta," 1368-1370, Copyright 1952, with permission
Medical Subject Headings (MeSH):
Obstetric Anesthesia and a Scorecard for Newborns, 1949-1958