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The Michael Heidelberger Papers

Title:
Chemical Studies on Bacterial Agglutination: III. A Reaction Mechanism and a Quantitative Theory pdf (1,422,939 Bytes) ocr (40,558 Bytes)
Chemical Studies on Bacterial Agglutination: III. A Reaction Mechanism and a Quantitative Theory
Description:
In this article, Heidelberger and Kabat continued their work to unravel the chemical processes of bacterial agglutination, the clumping together of antigen-bearing cells in the presence of antibodies called agglutinins. Here, they laid out a quantitative theory based on equations derived from the law of mass action that effectively showed that agglutination is analogous to the precipitin reaction. Their conclusion that agglutinins were not a distinct group of antibodies, but rather that agglutination and precipitation were separate functions of the same antibodies, overturned established conceptions of the agglutination process that had placed emphasis on the role of electrolytes and physical force.
Item is a photocopy.
Number of Image Pages:
18 (1,422,939 Bytes)
Date:
1937-06 (June 1937)
Creator:
Heidelberger, Michael
Kabat, Elvin A.
Source:
Periodical: Heidelberger, Michael, and Elvin A. Kabat. "Chemical Studies on Bacterial Agglutination: III. A Reaction Mechanism and a Quantitative Theory." Journal of Experimental Medicine 65, 6 (June 1937): 885-902. Article. 18 Images.
Publisher:
[Rockefeller Institute for Medical Research]
Rights:
Reproduced from the Journal of Experimental Medicine, 1937, 65, 885-902 by copyright permission of the Rockefeller University Press.
Subject:
Medical Subject Headings (MeSH):
Agglutination
Exhibit Category:
Antigens and Antibodies: Heidelberger and The Rise of Quantitative Immunochemistry, 1928-1954
Relation:
Metadata Record Chemical Studies on Bacterial Agglutination: II. The Identity of Precipitin and Agglutinin (May 1936) pdf (694,086 Bytes) ocr (20,244 Bytes)
/ps/access/DHBBBX.pdf
Unique Identifier:
DHBBCF
Document Type:
Articles
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Folder: [Selected articles collected by NLM]
Metadata Last Modified Date:
2006-06-15
Linked Data:
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