Quantitative Chemical Studies on Complement or Alexin: II. The Interrelation of Complement with Antigen-Antibody Compounds
and with Sensitized Red Cells
In this follow-up to their earlier paper on complement, Heidelberger, Alfred Weil, and Henry Treffers flesh out data they
had collected on the amount of antigen, antibody, hemolysin, and complement needed to create effective complement fixation
tests, which have become widely used procedures for the detection of antigens or antibodies. During complement fixation,
complement is consumed upon reaction with immune complexes bearing complement-fixing antibodies.
Item is a photocopy.
Number of Image Pages:
15 (1,433,079 Bytes)
1941-06 (June 1941)
Weil, Alfred J.
Treffers, Henry P.
Periodical: Heidelberger, Michael, Alfred J. Weil, and Henry P. Treffers. "Quantitative Chemical Studies on Complement or Alexin:
II. The Interrelation of Complement with Antigen-Antibody Compounds and with Sensitized Red Cells." Journal of Experimental
Medicine 73, 6 (June 1941): 695-709. Article. 15 Images.
[Rockefeller Institute for Medical Research]
Reproduced from the Journal of Experimental Medicine, 1941, 73, 695-709 by copyright permission of the Rockefeller University
Medical Subject Headings (MeSH):
Complement System Proteins
Antigens and Antibodies: Heidelberger and The Rise of Quantitative Immunochemistry, 1928-1954
Quantitative Chemical Studies on Complement or Alexin: I. A Method (June 1941)
[Lab notes on complement fixation experiments] [October-November 1940]