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The Michael Heidelberger Papers

Title:
Velocity of Combination of Antibody with Specific Polysaccharides of Pneumococcus pdf (789,353 Bytes) ocr (22,205 Bytes)
Velocity of Combination of Antibody with Specific Polysaccharides of Pneumococcus
Description:
In the early 1940s, Heidelberger turned his attention to studying immunological cross-reactions between type III and type VIII pneumococcal polysaccharide antigens, respectively, and antibodies formed against the other type of pneumococcal antigen (meaning that type III pneumococcal antigen reacted with type VIII anti-pneumococcal antibody, and type VIII pneumococcal antigen with type VIII anti-pneumococcal antibody). Immunological cross reactions occur when antibodies formed against one antigen react with another antigen that shares identical or closely related binding sites, called immunological determinants, with the first antigen. From such cross reactions scientists can deduce important details about the chemical composition of antigens and antibodies. In this paper, Heidelberger and Manfred Mayer reported their findings regarding the speed with which such cross reactions occurred.
Item is a photocopy.
Number of Image Pages:
8 (789,353 Bytes)
Date:
1942-05-01 (May 1, 1942)
Creator:
Mayer, Manfred M.
Heidelberger, Michael
Source:
Periodical: Mayer, Manfred M., and Michael Heidelberger. "Velocity of Combination of Antibody with Specific Polysaccharides of Pneumococcus." Journal of Biological Chemistry 143, 3 (1 May 1942): 567-574. Article. 8 Images.
Publisher:
[American Society for Biochemistry and Molecular Biology]
Rights:
This item is in the public domain. It may be used without permission.
Subject:
Medical Subject Headings (MeSH):
Antibodies
Polysaccharides
Pneumococcal Infections
Exhibit Category:
Antigens and Antibodies: Heidelberger and The Rise of Quantitative Immunochemistry, 1928-1954
Unique Identifier:
DHBBCL
Document Type:
Articles
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Folder: [Selected articles collected by NLM]
Metadata Last Modified Date:
2008-04-21
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