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The Michael Heidelberger Papers

Title:
The Human Antibody Response to Simultaneous Injection of Six Specific Polysaccharides of Pneumococcus pdf (260,676 Bytes) ocr (8,133 Bytes)
The Human Antibody Response to Simultaneous Injection of Six Specific Polysaccharides of Pneumococcus
Description:
During World War II, Heidelberger became involved in an effort by military physicians to develop a pneumonia vaccine, consisting of a combination of purified polysaccharides of four specific pneumococcal types, for the immunization of troops. For this article, Heidelberger and one of his wartime collaborators, Colin MacLeod, along with M. M. Di Lapi, studied how the body reacted if injected with more than four types of specific polysaccharides (a combination of four types were administered during the military field trial) at one time, namely with specific polysaccharides of the six most common types of pneumonia. The authors found that such a vaccine was as effective as one made of four pneumococcal polysaccharide antigens in stimulating an immune response.
Item is a photocopy.
Number of Image Pages:
4 (260,676 Bytes)
Date:
1948-09 (September 1948)
Creator:
Heidelberger, Michael
MacLeod, Colin M.
Di Lapi, Marie M.
Source:
Periodical: Heidelberger, Michael, Colin M. MacLeod, and Marie M. Di Lapi. "The Human Antibody Response to Simultaneous Injection of Six Specific Polysaccharides of Pneumococcus." Journal of Experimental Medicine 88, 3 (September 1948): 369-372. Article. 4 Images.
Publisher:
[Rockefeller Institute for Medical Research]
Rights:
Reproduced from the Journal of Experimental Medicine, 1948, 88, 369-372 by copyright permission of the Rockefeller University Press.
Subject:
Medical Subject Headings (MeSH):
Polysaccharides
Antibodies
Exhibit Category:
Antigens and Antibodies: Heidelberger and The Rise of Quantitative Immunochemistry, 1928-1954
Unique Identifier:
DHBBCQ
Document Type:
Articles
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Folder: [Selected articles collected by NLM]
Metadata Last Modified Date:
2008-04-21
Linked Data:
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