Skip to main contentU.S. National Library of MedicineU.S. National Library of Medicine

Profiles in Science
Pinterest badge Follow Profiles in Science on Pinterest!

The Michael Heidelberger Papers

Letter from Michael Heidelberger to the Bache Fund pdf (85,081 Bytes) transcript of pdf
Letter from Michael Heidelberger to the Bache Fund
In this grant application Heidelberger highlights the importance of the refrigerated centrifuge to the daily work of a microbiological laboratory. Heidelberger first proposed a design for a centrifuge with an insulated brine coil around it for cooling when he was working to produce large quantities of purified oxyhemoglobin at Rockefeller Institute in the early 1920s, a process during which the surrounding temperature had to be carefully controlled.
Number of Image Pages:
1 (85,081 Bytes)
1937-02-18 (February 18, 1937)
Heidelberger, Michael
Bache Fund
This item is in the public domain. It may be used without permission.
Medical Subject Headings (MeSH):
Exhibit Category:
The Making of an Immunologist: Heidelberger's Years at the Rockefeller Institute, 1912-1927
Box Number: 1
Folder Number: 5
Unique Identifier:
Document Type:
Letters (correspondence)
Grant proposals
Physical Condition:
Folder: MS C 245 (first finding aid)
February 18, 1937
I should be very happy to be awarded a grant from your Fund for the purchase of a new refrigerated centrifuge, an instrument which was first built at my suggestion in order to facilitate the preparation of oxyhemoglobin in its active state. The instrument we have now is becoming unfit for the heavy strain upon it, having been in almost daily use for many hours over a period of nine years. It has been indispensible for this laboratory's work on absolute methods of immunological analysis, the mechanism of immune reactions, the isolation of bacterial proteins and polysaccharides, the preparation of immune sera and the isolation of highly purified antibodies and in studies of the thyroid hormone.
One of the new and improved machines will greatly aid in continuing and facilitating the laboratory's work along these and other lines. The grant would also be of value to the Department of Bacteriology of the College of Physicians and Surgeons, Columbia University, for I should give the old machine to that department, where it would still be suitable for the intermittent, light-duty service to which it would be put.
The total cost of the centrifuge and the necessary accessories is . Should this appear excessive, I should be most grateful for as large a fraction of this sum as seems fitting.
Very truly yours
Michael Heidelberger
Metadata Last Modified Date:
Linked Data:
RDF/XML     JSON     JSON-LD     N3/Turtle     N-Triples