Letter from Marianne Grunberg-Manago to Maxine Singer
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1968-03-28 (March 28, 1968)
Institut Biologie Physico-Chimique
Original Repository: Library of Congress. Maxine Singer Papers
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Medical Subject Headings (MeSH):
Nucleic Acids, the Genetic Code, and Transposable Genetic Elements: A Life in Research
I am giving a series of courses to students and, as before, I have to say that maybe PNPase from L.arabinosus is in the particulate
part of the cell. I shall be going to Israel this September and I shall really be ashamed to repeat the same thing again;
so I am reminding you your promise to look into this. If you don't want to be bothered or don't have the time, I shall
be happy to do so and give you the results if you send me a strain.
Except for the courses, which are a pain in the neck, I am feeling fine. I have spent almost the last month writing a paper
on Q13 PNPase which has a 200 000 enzyme stimulated by manganese, as reported by Buchanan and which phosphorolyzes very poorly,
and a 100 000 enzyme which does phosphorolyze.
We also did electron micrographs of the enzyme, with Valentine of London, and PNPase seems to be an hexamer : two trimer forming
a triangle one over the other. We are now studying the subunits.
I hope to see you before, but in any case I am looking forward to seeing you in Greece.