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The Maxine Singer Papers

Title:
Letter from Maxine Singer to Erwin Chargaff pdf (46,927 Bytes) transcript of pdf
Letter from Maxine Singer to Erwin Chargaff
Number of Image Pages:
1 (46,927 Bytes)
Date:
1969-06-18 (June 18, 1969)
Creator:
Singer, Maxine
Recipient:
Chargaff, Erwin
Columbia University. College of Physicians and Surgeons
Source:
Original Repository: Library of Congress. Maxine Singer Papers
Rights:
Reproduced with permission of the Library of Congress.
Subject:
Medical Subject Headings (MeSH):
Poly U
Poly A
Exhibit Category:
Nucleic Acids, the Genetic Code, and Transposable Genetic Elements: A Life in Research
Relation:
Metadata Record Letter from Erwin Chargaff to Maxine Singer (June 26, 1969) pdf (50,537 Bytes) transcript of pdf
/ps/access/DJBBCH.pdf
Box Number: 3
Folder Number: 5
Unique Identifier:
DJBBCG
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Correspondence, 1955-2004, n.d.
SubSeries: Chronological
Folder: 1969 April-September
Transcript:
June 18, 1969
Dear Dr. Chargaff:
I read your interesting paper in the March issue of the PNAS. There is in fact another study of exactly the sort you describe "binding between ribopolymer and the complementary mononucleotide in the presence of an enzyme acting on the latter". The study is by Leon Heppel (JBC 238: 357, 1963) and deals with polynucleotide phosphorylase, and all possible base pairs.
In recent experiments with Dr. Robb Moses we confirmed the inhibition of the rate of poly U synthesis from UDP by poly A, and showed further, that, at several poly A concentrations, the enzyme was released from the inhibition when enough poly U was synthesized to complex the poly A completely as (A)n - 2(U)n.
I would very much appreciate receiving a reprint of the paper in the PNAS.
Thank you.
Sincerely yours,
Maxine Singer
Metadata Last Modified Date:
2010-11-12
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