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The Maxine Singer Papers

Letter from Maxine Singer to Georgio Bernardi pdf (67,840 Bytes) transcript of pdf
Letter from Maxine Singer to Georgio Bernardi
Number of Image Pages:
1 (67,840 Bytes)
1986-01-27 (January 27, 1986)
Singer, Maxine
Bernardi, Georgio
[Institut Jacques Monod]
Original Repository: Library of Congress. Maxine Singer Papers
Reproduced with permission of the Library of Congress.
Medical Subject Headings (MeSH):
Long Interspersed Nucleotide Elements
Exhibit Category:
Nucleic Acids, the Genetic Code, and Transposable Genetic Elements: A Life in Research
Box Number: 13
Folder Number: 4
Unique Identifier:
Document Type:
Letters (correspondence)
Physical Condition:
Series: Correspondence, 1955-2004, n.d.
SubSeries: Chronological
Folder: 1986 January
January 27, 1986
Dear Giorgio:
I am really disappointed to write and say that I cannot accept the invitation for the meeting in Crete in September. The program looks very exciting and unusual and I would very much like to be able to participate. Also, I have been hoping for an opportunity to meet Miklos, and this would have been a fine one. Finally, of course Crete would be marvelous at that time of year. But, we have planned for a long time to go directly from the FEBS meeting in Berlin at the end of August to visit with Amy, who will be spending a year in the middle east working on her doctoral thesis. In particular, she will have been in Istanbul from May on and she and Dan and I are counting on a visit in Turkey. Thank you very much for the invitation.
Thus far our efforts to identify a polypeptide encoded by the LINE-l sequence in teratocarcinoma cells have yielded nothing. Moreover, the cDNA clones from the poly A-cytoplasmic RNA from those cells look to be almost, though not quite, as big a mixture of sequences as the genomic LINE-1 sequences. They are a particular subset of the genomic sequences, but not all of them are coding as some have stop codons and other breaks in the open reading frame. But some may well be open throughout and we are now trying to make improved antibodies with long polypeptides made from the cDNA's in E. coli. It is turning out to be quite a struggle.
With best wishes to you and Gabriella and the children. We think often of your son in South Africa and wonder how things are going with him during these difficult days.
Maxine Singer
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