Skip to main contentU.S. National Library of MedicineU.S. National Library of Medicine


Profiles in Science
   
Pinterest badge Follow Profiles in Science on Pinterest!

The William Osler Papers

Title:
Short Notes on a Course of Practical Physiology by Dr. Burdon-Sanderson at University College London, 1872-73 pdf (569,651 Bytes) transcript of pdf
Short Notes on a Course of Practical Physiology by Dr. Burdon-Sanderson at University College London, 1872-73
Description:
Item is handwritten.
Number of Image Pages:
5 (569,651 Bytes)
Date Supplied:
7, 10-11 October 1872
Creator:
Osler, William
Source:
Original Repository: Osler Library of the History of Medicine, McGill University. Bibliotheca Osleriana
BO #7666
Rights:
This item is in the public domain. It may be used without permission.
Subject:
Medical Subject Headings (MeSH):
Physiology
Exhibit Category:
Medical Education and Early Career, McGill University, 1870-1884
Unique Identifier:
GFBBGP
Document Type:
Notes
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Transcript:
Short Notes on a course of Practical Physiology
By
Dr. Burdon-Sanderson
at
University College
London
1872-73
Wm. Osler, M.D.
[END PAGE ONE]
[BEGIN PAGE TWO]
Oct 7th
Examination of inflamed anterior chamber of eye of frog and of lymph sac. They were prepared in the following way. A thread was passed into the anterior chamber and through the cornea, one end then cut short and pulled within the other like wire. A portion of frogs skin soaked in ammonia was then inserted into the lymph sac over the cervical region and pushed down towards the lumbar and there left. The animal is ready for examination in two days. To remove the pus from eye, prick it with a [triangle] knife and then quickly insert a capillary pipette. Numerous pus globules are found, all of them exhibiting very active movements, changing shapes rapidly, containing granules, vacuoles, and a nucleous.
[END PAGE TWO]
[BEGIN PAGE THREE]
The cornea is apparently not much altered but when examined in the fibrous stroma between the epithelial layers are found "wanderers" exhibiting movement. Treat the lymph sac in following way, dissect carefully off a thin year, taking care not to touch the endothelium (and it is best done under water) and brush it with a solution of AgNO3 [silver nitrate] 1/4 percent, then place it in the sunlight for a short time, on examination it will be found that the outlines of the cells are stained and the pus globules are coloured.
10th -- Examination of omentum of rabbit 3 days after injection with ammoniated milk. After being brushed with solution of AgNO3 and exposed to light, cut square pieces and examine, floating them onto the glass slips and taking great care to obtain the specimen free from
[END PAGE THREE]
[BEGIN PAGE FOUR]
folds and creases. The serous epithelium is seen mapped out by the AgNO3, the cells containing many minute particles looking like fine oil globules, but may be the deposit of AgNO3 in them. Vessels of three kinds are seen, veins, arteries, and lymphatics, the latter being the interesting ones. They seem to be found more in the track of the vessels than in the interspaces between them and have their endothelium well brought out by the staining.
11th -- Continued examination of inflamed and health omentum of rabbit. The lymphatics as shown by the AgNO3 method present an imbricated appearance due to the stained outline of the endothelium. On serious surfaces generally the relation between parts is supposed by recent observers to be as follows: Beneath the epithelium ramify
[END PAGE FOUR]
[PAGE FIVE]
the lympatics and capillaries together with a system of branched nucleated cells which communicate with both the lymphatics and the adjacent ones. Opening onto the serous surfaces are certain bodies called stomata, of which there are two kinds, the true and the false.
Metadata Last Modified Date:
2013-10-21
Linked Data:
RDF/XML     JSON     JSON-LD     N3/Turtle     N-Triples