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The Martin Rodbell Papers

Title:
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: V. An Obligatory Role of Guanyl Nucleotides in Glucagon Action pdf (892,231 Bytes) ocr (29,478 Bytes)
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: V. An Obligatory Role of Guanyl Nucleotides in Glucagon Action
Description:
The fifth in a now-classic series of five articles in which Rodbell concluded that GTP was likely the active biological factor in separating glucagon from the cell's receptor, which had important implications for the treatment of various disorders and diseases. In the last two articles of this series, Rodbell demonstrated that GTP affected the binding of glucagon to its receptors and was necessary for glucagon to activate adenyl cyclase, an important component of some intracellular signaling pathways.
Number of Image Pages:
6 (892,231 Bytes)
Date:
1971-03-25 (March 25, 1971)
Creator:
Rodbell, Martin
Birnbaumer, Lutz
Pohl, Stephen L.
Krans, Hendrik Michiel Jan
Source:
Periodical: Rodbell, Martin, Lutz Birnbaumer, Stephen L. Pohl, and Hendrik Michiel Jan Krans. "The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: V. An Obligatory Role of Guanyl Nucleotides in Glucagon Action." Journal of Biological Chemistry 246, 6 (25 March 1971): 1877-1882. Article. 6 Images.
Publisher:
American Society for Biochemistry and Molecular Biology
Rights:
Reproduced with permission of the American Society for Biochemistry and Molecular Biology.
Subject:
Medical Subject Headings (MeSH):
Adenylyl Cyclases
Binding Sites
Cell Membrane
Guanine Nucleotides
Exhibit Category:
Signal Transduction and the Discovery of G-Proteins, 1969-1980
Relation:
Metadata Record The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: I. Properties (March 25, 1971) pdf (1,195,715 Bytes) ocr (39,101 Bytes)
/ps/access/GGAAAW.pdf
Metadata Record The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: II. Comparison Between Glucagon- and Fluoride-Stimulated Activities (March 25, 1971) pdf (501,891 Bytes) ocr (16,814 Bytes)
/ps/access/GGAAAX.pdf
Metadata Record The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: III. Binding of Glucagon: Method of Assay and Specificity (March 25, 1971) pdf (1,971,973 Bytes) ocr (63,171 Bytes)
/ps/access/GGAAAY.pdf
Metadata Record The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: IV. Effects of Guanyl Nucleotides on Binding of 125 I-Glucagon (March 25, 1971) pdf (927,809 Bytes) ocr (29,777 Bytes)
/ps/access/GGAAAZ.pdf
Box Number: 19
Folder Number: 11
Unique Identifier:
GGAABA
Document Type:
Articles
Language:
English
Format:
application/pdf
image/tif
Series: Laboratory Work and Research Publications, 1965-1997
SubSeries: Reprints
Folder: "The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. V. An obligatory role" (1971) TO "G-proteins have characteristics of cytoskeletal proteins: A basis for the programmable messenger theory" (1988)
Metadata Last Modified Date:
2016-06-02
Linked Data:
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