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The Julius Axelrod Papers

Title:
Studies on Sympathomimetic Amines. I. The Biotransformation and Physiological Disposition of l-Ephedrine and l-Norephedrine pdf (1,063,369 Bytes) ocr (31,065 Bytes)
Studies on Sympathomimetic Amines. I. The Biotransformation and Physiological Disposition of l-Ephedrine and l-Norephedrine
Description:
This article was the first in a series of papers by Axelrod on the role played in the body by sympathetic amines, a broad class of chemicals that mimic the actions of the sympathetic nervous system and have an amine basic structure. Through a variety of tests on several animals, Axelrod found two primary processes, demethylation and hydroxylation, that metabolically transformed ephedrine. He also noted that various animal species showed considerable differences in the relative importance of the two metabolic routes.
Number of Image Pages:
12 (1,063,369 Bytes)
Date:
1953-09 (September 1953)
Creator:
Axelrod, Julius
Source:
Periodical: Axelrod, Julius. "Studies on Sympathomimetic Amines. I. The Biotransformation and Physiological Disposition of l-Ephedrine and l-Norephedrine." Journal of Pharmacology and Experimental Therapeutics 109, 1 (September 1953): 62-73. Article. 12 Images.
Publisher:
American Society for Pharmacology and Experimental Therapeutics
Rights:
Reproduced with permission of the American Society for Pharmacology and Experimental Therapeutics.
URL: http://www.aspet.org/Exit
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Subject:
Medical Subject Headings (MeSH):
Biotransformation
Sympathomimetics
Exhibit Category:
Work on the Sympathomimetic Amines, 1946-1958
Relation:
Metadata Record Studies on Sympathomimetic Amines. II. The Biotransformation and Physiological Disposition of D-Amphetamine, D-P-Hydroxyamphetamine and D-Methamphetamine (March 1954) pdf (1,146,989 Bytes) ocr (32,431 Bytes)
/ps/access/HHAAAH.pdf
Metadata Record The Enzymatic Deamination of Amphetamine (Benzedrine) (June 1955) pdf (987,525 Bytes) ocr (27,459 Bytes)
/ps/access/HHAAAI.pdf
Box Number: 22
Folder Number: 4
Unique Identifier:
HHAAAG
Document Type:
Articles
Language:
English
Format:
application/pdf
image/tif
Series: Writings and Publications, 1910-2003
SubSeries: Articles by Axelrod
SubSubSeries: Loose Reprints
Folder: Articles 1-280, 1948-1969
Metadata Last Modified Date:
2016-05-26
Linked Data:
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