Letter from John E. Bruno to Marshall W. Nirenberg and J. Heinrich Matthaei
In this letter, a man from Wisconsin responds to an article in Science Digest describing Marshall Nirenberg's work in
genetics. Bruno asks Nirenberg and Matthaei if their work might explain the cause of albinism and recommends an experiment
for the researchers.
Item is handwritten.
Number of Image Pages:
2 (127,437 Bytes)
1962-03-23 (March 23, 1962)
Bruno, John E.
Nirenberg, Marshall W.
Matthaei, J. Heinrich
Courtesy of Marshall W. Nirenberg.
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In my April issue of Science Digest an article was written on the wonderfull [sic] work use are doing on genetics and Metabolic
Now the reason I write is to inquire of a metabolistic [sic] problem I have, Albinoism. In the article it states of the work
uses are doing on herditary [sic] Materials DNA and RNA. In your experiments have you found the cause of Albinoism? Have uses
done any experiments with Albino mice? Is there any way of inducing pigment formations?
My name is John E. Bruno. I am of Italian extraction. I have 20/200 vision. I have ben [sic] to a number of Oculist [sic]
and their diagnosis is of the same pattern a lack of pigment in the retina. My O.D. has not ben [sic] able to give me any
anatomical improvement. Is there a chemical that can be induced [sic] in the blood stream to stain the retina?
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Drs. I have an experiment which would be very interesting to work with! Understanding that the retina is a continuation of
the brain and being a very complex mechanism to work with! My experiment deals with employing charged particles of chemicals
that would be exceptable [sic] to tissue. Using a screen and a plate. The screen is charged and the solid metal plate being
of opposite polarity from that of the screen Placing the chemicals in front of the screen the chemicals particles become charged
and are drawn to the plate. The retina being between the chemical and plate becomes impergnated [sic].
Hoping to receive an answer to this letter I remain