The Dependence of Cell-Free Protein Synthesis in E. coli upon RNA Prepared from Ribosomes
In this article, the work for which was supported by a NATO post-doctoral fellowship, Marshall Nirenberg and Heinrich Matthaei
reveal their stable cell-free system in which their protein synthesis studies would culminate with the landmark poly-U experiments.
Here, Nirenberg and Matthaei present their finding that incorporation of amino acids into protein is dependent on the addition
of ribosomal RNA preparations.
Item is a photocopy.
Number of Image Pages:
5 (321,409 Bytes)
Matthaei, J. Heinrich
Nirenberg, Marshall W.
Periodical: Matthaei, J. Heinrich, and Marshall W. Nirenberg. "The Dependence of Cell-Free Protein Synthesis in E. coli upon RNA Prepared
from Ribosomes." Biochemical and Biophysical Research Communications 4, 6 (1961): 404-408. Article. 5 Images.
Reproduced with permission of the Academic Press.
Synthetic RNA and the Poly-U Experiments, 1959-1962