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The Marshall W. Nirenberg Papers

Letter from Francois Jacob to Marshall W. Nirenberg pdf (49,742 Bytes) transcript of pdf
Letter from Francois Jacob to Marshall W. Nirenberg
By 1970, Marshall Nirenberg had turned his attention to neurobiology and developed valuable microassays for enzyme study. In this letter, Jacob requests information from Nirenberg on techniques and protocols for enzyme and transmitter assays in mouse nervous system and mouse cell culture research. He informs Nirenberg that he has left his own work on nematodes and asks what is new with Nirenberg's own nematode or neuroblastoma research.
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1 (49,742 Bytes)
1970-01-30 (January 30, 1970)
Jacob, Francois
Nirenberg, Marshall W.
Reproduced with permission of Francois Jacob.
Exhibit Category:
Neuroblastoma Research, 1967-1976
Box Number: 4
Folder Number: 42
Unique Identifier:
Accession Number:
Document Type:
Letters (correspondence)
Physical Condition:
Series: Series II: Correspondence, 1953-1993
Folder: General, 1953-1977
30 janvier 1970
Dear Marshall,
I understand from the paper of Gordon Sato in PNAS that you have developed a series of elegant micro-assays for the enzymes of catecholamine, acetylcholine, serotonin and GABA biosynthesis and catabolism.
I have left the nematodes which do not allow me to do what I would like. I am turning now to work on mouse nervous system and mouse cell cultures. I have of course no experience in the field, but I would very much like to have in hand the techniques for the study of the transmitters. If you have no objection, I would be very grateful for a detailed protocol for these enzyme and transmitter assays.
What is new with nematodes with mouse neuro-blastoma and other cells in your lab? Is there any chance to see you around Paris in the near future?
With very best wishes,
Yours sincerely,
Francois Jacob
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