Regulation of Acetylcholinesterase in Neuroblastoma Cells
This article is one of the first published reports of Marshall Nirenberg's work during his transitional move toward neurobiological
investigation. Experimental findings in the article show that when tumor cells shift from the dividing to the non-dividing
state, they are influenced by the expression of a set of genetic characteristics required for neuron differentiation. As
progeny cells remained committed to a program of neuron differentiation, the authors anticipated implications for the study
of healthy neurons--the "possibility" that "normal sympathetic neuroblasts are also inversely committed to a pattern
of neuronal differentiation."
Item is a photocopy.
Number of Image Pages:
7 (749,908 Bytes)
1970-10 (October 1970)
Blume, Arthur J.
Farber, John L.
Rosenberg, Roger N.
Nirenberg, Marshall W.
Periodical: Blume, Arthur J., F. Gilbert, S. Wilson, John L. Farber, Roger N. Rosenberg, and Marshall W. Nirenberg. "Regulation of
Acetylcholinesterase in Neuroblastoma Cells." Proceedings of the National Academy of Sciences of the United States of
America 67, 2 (October 1970): 786-792. Article. 7 Images.
National Academy Press
Reproduced with permission of Marshall W. Nirenberg.