Opiate Receptors as Regulators of Adenylate Cyclase
This monograph reports on the progress of Nirenberg's neuroblastoma research. The authors find that morphine inhibits
enzymatic activity and enzyme production levels. Additionally, hybrid cells show that the number of opiate receptors mediates
inhibition of morphine. Results suggest that because drugs may act as enzyme inducers, recovery from the addicted state requires
return of adenylate cyclase activity to normal levels.
Item is a photocopy.
Number of Image Pages:
6 (508,637 Bytes)
1975-05-24 (May 24, 1975)
Klee, Werner A.
Sharma, Shail K.
Nirenberg, Marshall W.
Monograph: Klee, Werner A., Shail K. Sharma, and Marshall W. Nirenberg. "Opiate Receptors as Regulators of Adenylate Cyclase."
The Opiate Narcotics, Neurochemical Mechanisms in Analgesia and Dependence. Pergamon Press, 24 May 1975. Pp. 117-122. Excerpt.
Monograph. 6 Images.