Skip to main contentU.S. National Library of MedicineU.S. National Library of Medicine

Profiles in Science
Pinterest badge Follow Profiles in Science on Pinterest!

The Marshall W. Nirenberg Papers

Letter from Frank H. Ruddle to Marshall W. Nirenberg pdf (60,723 Bytes) transcript of pdf
Letter from Frank H. Ruddle to Marshall W. Nirenberg
Ruddle updates Nirenberg on the work of other scientists engaged in neuroblastoma related research, such as John Minna and Art Morris, and expresses an interest in obtaining protocols for research.
Number of Image Pages:
1 (60,723 Bytes)
1971-03-17 (March 17, 1971)
Ruddle, Frank H.
Yale University
Nirenberg, Marshall W.
Reproduced with permission of Frank H. Ruddle.
Exhibit Category:
From Neuroblastoma to Homeobox Genes, 1976-1992
Box Number: 4
Folder Number: 43
Unique Identifier:
Accession Number:
Document Type:
Letters (correspondence)
Physical Condition:
Series: Series II: Correspondence, 1953-1993
Folder: General, 1953-1977
March 17, 1971
Dear Marshall:
It was good seeing you and hearing about your work with the neuroblastoma line at the NRP Conference. John Minna expressed an interest in learning about our techniques for identifying cell line specific chromosomes utilizing heterochromatin staining techniques. Mr McMorris has sent to him a preprint of an article in press on this subject by Ruddle & Chen. We have also sent him our protocol for visualization of phosphoglucomutase electrophoretic differences between Neuro and L-strain cell populations.
As you know, Art McMorris in our laboratory has some hybrid cell lines between neuro and mouse L cell lines. We are particularly interested in testing these hybrid clones for differentiated functions - especially neuro associated enzymes. It would be a great help to us if we could obtain your protocols for tyrosine hydroxylase, choline acetylase, and glutamate decarboxylase. If it is too much trouble to send these, I can stop by possibly next Thursday and pick them up.
Yours sincerely
Frank H. Ruddle
Metadata Last Modified Date:
Linked Data:
RDF/XML     JSON     JSON-LD     N3/Turtle     N-Triples