Wolfe, from the Division of Endocrinology at the Children's Hospital of Harvard Medical School requests Brn-2 cDNA from
Nirenberg's laboratory for use in examining the role of Brn-2 in the regulation of gene expression. A hand note at the
top of the letter from Nirenberg approves the request.
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1995-12-01 (December 1, 1995)
Harvard Medical School. Children's Hospital
Nirenberg, Marshall W.
Reproduced with permission of the Harvard University Medical School Children's Hospital.
[Handwritten note: 12-1-95 Yoshi -- would you send Brn-2 genomic DNA clone to Wolfe. Marshall]
Dear Dr. Nirenberg,
We are interested in obtaining the Brn-2 cDNA from your laboratory for use in examining the role of Brn-2 in the regulation
of gonadotropin-releasing hormone (GnRH) gene expression. Evidence obtained from our NLT and Gn11 cell lines, both of which
are neural GnRH expressing cell lines (Radovick et al. PNAS (1991) 88:3402-3406), suggests that Brn-2 might play an important
role in this process.
We would, of course, acknowledge your contribution in any publications that resulted from the use of this cDNA, and we would
not give this cDNA to anyone else without your permission.
If you have any questions feel free to call (617-355-6957) or fax (617-730-0741) us. Thank you very much.