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The Victor A. McKusick Papers

Title:
Letter from James L. Reynolds to Victor A. McKusick pdf (73,636 Bytes) transcript of pdf
Letter from James L. Reynolds to Victor A. McKusick
Number of Image Pages:
1 (73,636 Bytes)
Date:
1971-04-21 (April 21, 1971)
Creator:
Reynolds, James L.
Tulane University. School of Medicine
Recipient:
McKusick, Victor A.
Source:
Original Repository: Alan Mason Chesney Medical Archives. Victor Almon McKusick Collection
Rights:
Reproduced with permission of James L. Reynolds.
Subject:
Medical Subject Headings (MeSH):
Heart Defects, Congenital
Fetal Growth Retardation
Exhibit Category:
The Bar Harbor Course and "McKusick's Catalog," 1960-1980
Relation:
Metadata Record Letter from James L. Reynolds to Victor A. McKusick (March 11, 1971) pdf (64,864 Bytes) transcript of pdf
/ps/access/JQBBBJ.pdf
Metadata Record Letter from Victor A. McKusick to James L. Reynolds (March 17, 1971) pdf (31,169 Bytes) transcript of pdf
/ps/access/JQBBBH.pdf
Unique Identifier:
JQBBBG
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Transcript:
April 21, 1971
Dear Dr. McKusick:
Thank you for your letter of March 17th stating your wish that I present data on two topics: Heart Disease in Mongolism and Incidence of Heart Disease in Babies of Low Birth Weight. I also received the tentative program of the Fourth Conference on the Clinical Delineation of Birth Defects, June 7 to 11, 1971. The program looks very good. In a previous letter I tried to indicate that I was not happy with the data I had relative to heart disease in mongolism. I have since reviewed these data more carefully and am even more certain that I should not present them. The data are fragmentary and I do not believe that I have anything to add to the information already available. I would prefer not to present or publish on this topic.
I do believe the other topic, Congenital Cardiac Defects in Low-Birth-Weight, Full-term Babies, i.e. babies with intrauterine growth retardation, I.G.R., will be appropriate and of interest. Practically nothing has been reported on this topic. My prospective and retrospective study groups include a total of 451 children with congenital heart disease. Sixty-two of these (14%) had I.G.R. A variety of cardiac defects were found in these I.G.R. babies. The incidence of one defect, aortic stenosis, was, however, unusually high, 13%. This is in contrast to the 5.5% incidence of aortic stenosis found in those without I.G.R. The data suggests a possible relationship between I.G.R. and aortic stenosis.
Please let me know if this is satisfactory with you that I publish or present and publish only the congenital heart disease -- intrauterine growth retardation topic -- and not that of mongolism and heart disease. If you prefer that I not attend as a participant under these circumstances, I shall certainly understand.
With best regards,
Yours truly,
James L. Reynolds, M.D.
Metadata Last Modified Date:
2008-12-15
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