In this article, Anfinsen, Schecter, and Chen reported one of the first direct measurements of the folding of proteins to
their native conformation from a disordered state by use of a stopped-flow spectrofluorometer. Understanding protein folding
was seen as an essential intermediate step to obtaining the information of the genetic code for the biological function of
the corresponding protein or polypeptide chain.
Number of Image Pages:
2 (351,842 Bytes)
1970-02-06 (February 6, 1970)
Schechter, Alan N.
Chen, Raymond F.
Anfinsen, Christian B.
Periodical: Schechter, Alan N., Raymond F. Chen, and Christian B. Anfinsen. "Kinetics of Folding of Staphylococcal Nuclease."
Science 167, (6 February 1970): 886-887. Article. 2 Images.
American Association for the Advancement of Science