The Use of Affinity Chromatography in the Study of Protein Folding
This article, which includes handwritten notes by Anfinsen, provided an overview of the use of affinity chromatography in
the study of protein folding and its importance for vaccine production. Anfinsen briefly reviewed the use of affinity chromatography
as a tool in the study of the interaction between peptides and antibodies, noting that at times the technique revealed that
fragments of a protein molecule bind with monospecific antibodies, thus indicating that those fragments, which otherwise appeared
to lack structure, occupied an ordered structure for at least a portion of their existence.
Number of Image Pages:
7 (455,432 Bytes)
Anfinsen, Christian B.
Editor: Chaiken, I.
Editor: Wilchek, M.
Editor: Parikh, I.
Monograph: Anfinsen, Christian B. "The Use of Affinity Chromatography in the Study of Protein Folding." Affinity Chromatography
and Biological Recognition, edited by I. Chaiken, M. Wilchek, and I. Parikh. Academic Press, 1983. Pp. 355-361. Article. 7
Reproduced with permission of the Academic Press.
Medical Subject Headings (MeSH):
Molecular Engineering and Affinity Chromatography, 1959-1972