Comparison of beta-Galactosidases from Normal and Operator Constitutive Strains of E. Coli
This brief article, Steers, Craven, and Anfinsen reported the results of various physical and chemical studies involving enzymatic
comparisons of the lactose splitting enzyme beta-galactosidases from the "normal," or "wild type," and "operator
constitutive" strains of E. coli. They determined that no detectable differences could be found between the two protein
preparations, and concluded that the operator locus, the region of DNA at one end of an operon that acts as the binding site
for repressor proteins, did not specify any part of the structure of the beta-galactosidase molecule.
Number of Image Pages:
8 (1,076,211 Bytes)
1965-10 (October 1965)
Steers, Edward Jr
Craven, Gary R.
Anfinsen, Christian B.
Periodical: Steers, Edward Jr, Gary R. Craven, and Christian B. Anfinsen. "Comparison of beta-Galactosidases from Normal and Operator
Constitutive Strains of E. Coli." Proceedings of the National Academy of Sciences of the United States of America 54,
4 (October 1965): 1174-1181. Article. 8 Images.