Nuclease-T: An Active Derivative of Staphylococcal Nuclease Composed of Two Noncovalently Bonded Peptide Fragments
This is one of many articles produced by Anfinsen's research team and others on the factors contributing to the translation
of the genetic message for a particular protein backbone. Taniuchi, Sodja, and Anfinsen determined that such a translation
was no longer possible if the linear information had been manipulated through the deletion of amino acid residues. However,
they did find that some proteins that they termed "recombining systems" could be cleaved into two, or even three,
fragments that recombined through non-covalent forces to yield biologically active structures with physical properties very
similar to those of the parent protein molecules.
Number of Image Pages:
8 (958,617 Bytes)
1967-09 (September 1967)
Anfinsen, Christian B.
Periodical: Taniuchi, Horoshi, Christian B. Anfinsen, and Ann Sodja. "Nuclease-T: An Active Derivative of Staphylococcal Nuclease
Composed of Two Noncovalently Bonded Peptide Fragments." Proceedings of the National Academy of Sciences of the United
States of America 58, 3 (September 1967): 1235-1242. Article. 8 Images.