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The Christian B. Anfinsen Papers

Title:
Human Lymphoblastoid Interferon: Purification, Amino Acid Composition, and Amino-Terminal Sequence pdf (778,952 Bytes) ocr (24,519 Bytes)
Human Lymphoblastoid Interferon: Purification, Amino Acid Composition, and Amino-Terminal Sequence
Description:
This article was the result of collaboration between various members of Anfinsen's lab at the NIAMD with Hunkapiller and Hood at Caltech. In it, they addressed the difficult problem of determining the amino acid sequence of Human Lymphoblastoid Interferon (HuIFN-alpha). Earlier attempts to sequence the amino-terminal portion of this molecule using conventional methods failed due to insufficient quantities of interferon. Through this collaboration, Anfinsen's lab developed a microsequencer, a technology that allowed them to obtain amino acid sequence data on 10 to 20 picomoles of protein. Because of this, they were able to successfully determine the amino-terminal amino acid sequence of the major component of human lymphoblastoid interferon (HuIFN-alpha).
Item is a photocopy.
Number of Image Pages:
9 (778,952 Bytes)
Date:
1980
Creator:
Zoon, Kathryn C.
Smith, Mark E.
Bridgen, Pamela J.
Zur Nedden, Dorothy
Miller, Dorothea M.
Anfinsen, Christian B.
Source:
Periodical: Zoon, Kathryn C., Mark E. Smith, Pamela J. Bridgen, Dorothy Zur Nedden, Dorothea M. Miller, and Christian B. Anfinsen. "Human Lymphoblastoid Interferon: Purification, Amino Acid Composition, and Amino-Terminal Sequence." Annals of the New York Academy of Sciences 350, (1980): 390-398. Article. 9 Images.
Publisher:
New York Academy of Sciences
Rights:
Reproduced with permission of the New York Academy of Sciences.
URL: http://www.nyas.org/Exit
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Subject:
Medical Subject Headings (MeSH):
Interferons
Amino Acids
Amino Acid Sequence
Lymphocytes
Box Number: 28
Folder Number: 6
Unique Identifier:
KKBBLM
Document Type:
Articles
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Reprints and Research Publications, 1950-1993
SubSeries: Anfinsen Publications, 1954-1993
SubSubSeries: Numbered Reprints
Folder: 211-220
Metadata Last Modified Date:
2006-06-12
Linked Data:
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