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The Christian B. Anfinsen Papers

Title:
Reductive Cleavage of Disulfide Bridges in Ribonuclease pdf (322,541 Bytes) ocr (10,435 Bytes)
Reductive Cleavage of Disulfide Bridges in Ribonuclease
Description:
This article was the first of many studies that were generally concerned with the eventual total synthesis of the protein. It contained several original observations that would lead to the conclusion that the refolding of the ribonuclease molecule after full denaturation by reductive cleavage of its four disulfide bonds required that only one of the one hundred five possible pairings of eight sulfhydryl groups to form four disulfide linkages take place.
Number of Image Pages:
3 (322,541 Bytes)
Date:
1957-04-12 (April 12, 1957)
Creator:
Sela, Michael
White, Frederick H.
Anfinsen, Christian B.
Source:
Periodical: Sela, Michael, Frederick H. White, and Christian B. Anfinsen. "Reductive Cleavage of Disulfide Bridges in Ribonuclease." Science 125, 3250 (12 April 1957): 691-692. Article. 3 Images.
Publisher:
American Association for the Advancement of Science
Rights:
Courtesy of Science Magazine.
This item is in the public domain. It may be used without permission.
Unique Identifier:
KKBBLT
Document Type:
Articles
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Metadata Last Modified Date:
2006-04-10
Linked Data:
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