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The Rosalind Franklin Papers

Title:
Letter from Robley Williams to Rosalind Franklin pdf (46,811 Bytes) transcript of pdf
Letter from Robley Williams to Rosalind Franklin
Description:
Robley Williams was one of many virus researchers that Franklin visited during her 1954 trip to the United States. In this letter, he brought her up to date on developments in his laboratory, which was working with reconstituted TMV.
Number of Image Pages:
1 (46,811 Bytes)
Date:
1955-10-10 (October 10, 1955)
Creator:
Williams, Robley
University of California, Berkeley
Recipient:
Franklin, Rosalind
Source:
Original Repository: Churchill Archives Centre. The Papers of Rosalind Franklin
Rights:
Reproduced with permission of Robley C. Williams Jr.
Subject:
Medical Subject Headings (MeSH):
Tobacco Mosaic Virus
RNA
Exhibit Category:
Envisioning Viruses: Birkbeck College, London, 1953-1958
Folder Number:
2/35
Unique Identifier:
KRBBDK
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Series: Work on Tobacco Mosaic Virus (TMV)
Folder: Correspondence Relating to Franklin's First Visit to Berkeley, California, Mar. 1952 - Mar. 1958
Transcript:
October 10, 1955
Dear Rosalind:
I have spoken to Heinz Fraenkel-Conrat some time ago about sending you some reconstituted TMV, and I hope he has done so by now. If not, the materials should soon be coming along.
Roger Hart has just found out, by way of a confirmation of the earlier work by H.F.C. and R.C.W., that his partially degraded material (infectivity less than 10% of intact TMV) can be reactivated to almost full infectivity by simple mixture with TMV protein. This type of reactivation has the advantage that there is no worry about possible contaminating virus in the RNA preparation, a matter about which H.F.C. and R.C.W. have never felt completely sure. Hart works at higher levels of infectivity where the risk of significant contamination in the protein fraction is negligible, and, of course, he uses no purified RNA.
It will be good to see you in late March.
Regards,
Robley C. Williams
Metadata Last Modified Date:
2008-09-23
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