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The Rosalind Franklin Papers

Letter from Rosalind Franklin to Barry Commoner pdf (75,910 Bytes) transcript of pdf
Letter from Rosalind Franklin to Barry Commoner
During her 1954 visit to the United States, Franklin visited many virus researchers who would subsequently collaborate with her on projects involving virus structures. Barry Commoner sent her samples of a protein he called B8, to compare with the x-ray diffraction studies of TMV protein. They subsequently published several articles together. In this letter she told Commoner about her latest results on B8, and the note she had prepared to publish in Nature, asking for his comments as quickly as possible.
Number of Image Pages:
1 (75,910 Bytes)
1955-03-09 (March 9, 1955)
Franklin, Rosalind
Commoner, Barry
Washington University. Henry Shaw School of Botany
Original Repository: Churchill Archives Centre. The Papers of Rosalind Franklin
Reproduced from the Franklin Collection at the Churchill Archives Centre with the permission of the copyright holder.
Medical Subject Headings (MeSH):
Tobacco Mosaic Virus
X-Ray Diffraction
Exhibit Category:
Envisioning Viruses: Birkbeck College, London, 1953-1958
Folder Number:
Unique Identifier:
Document Type:
Letters (correspondence)
Series: Work on Tobacco Mosaic Virus (TMV)
Folder: Correspondence Regarding Franklin's Research, 1953-1958
9th March, 1955
Dear Dr. Commoner,
As you will see from the enclosed, I have now taken photographs of dry B8 and written a short note on the result. I am afraid this may seem rather hasty, but the advantage of sending something to Nature immediately is that it would appear immediately following the Rich, Dunitz, and Newmark note, of which I am sending you a copy. I shall, of course wait for your comments before actually sending it to Nature, but I have warned the Editor that it is on the way. If you would care to add a bit more information about B8 and its relationship to polymerised X, and make the thing a joint publication, I should be very glad if you would send me what you would like to add, and either make or leave me to make the appropriate modifications in what I have written.
I have not yet got prints of my photographs, but the results will look something like this
I have just received from Takahashi a sample of protein X. It is apparently unpolymerised, so I shall put it at pH 5 and see what I can get from it. I am anxious to know how much of the difference between Rich's results and mine is due to method and how much to the material.
Reading your papers and Takahashi's, there seems to be one point of difference between B8 and polymerised X on which you make no comment. You state that B3 polymerises irreversibly to B8, whereas Takahashi states that the polymerisation of X at pH 5 is reversed to pH 7.
I should be most grateful if you would let me have your comments on (and possible additions to) my note as quickly as possible.
Yours sincerely,
Rosalind Franklin
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