In this letter to Watson, Franklin discussed the progress of her work on TMV. Within the next year, she would establish that
the TMV protein did have a groove, and that this is where the virus RNA was located.
Number of Image Pages:
1 (75,748 Bytes)
1955-03-07 (March 7, 1955)
Watson, James D.
California Institute of Technology. Kerckhoff Laboratories of Biology
Original Repository: Churchill Archives Centre. The Papers of Rosalind Franklin
Reproduced from the Franklin Collection at the Churchill Archives Centre with the permission of the copyright holder.
Many thanks for your letter. Robley Williams's new E.M. work is certainly exciting and convincing. I had heard about
the visible threads, from several sources, but not about the work on polymerised protein X.
I've been doing various things since I last wrote, and hope to write up some of them soon, and send a manuscript to you.
I've been developing the idea of a grooved contour and estimate the depth of the groove, to be of the order 15 A. This
leads me to suspect a reversal of the normal size distribution between the 2nd and 3rd non-origin maxima on the equation.
It is not clear from your letter whether this agrees with Casper's signs or not. Do you include the central maxima in
the sign distribution you give? My guess is 0(+), l(-), 2(+), 3(+). It would be nice to know whether this is the same as
Caspar's series, which was derived by totally different reasoning.
I have also got some good photographs from cucumber virus (from Knight) and from a different strain of TMV (2 from Siegel
at U.C.L.A.) They show some quite interesting points of difference.
More recently I've had some of Commoner's B8 which does quite exciting things. It expands like a stretched spring
when in water - by about 15 percent.