Skip to main contentU.S. National Library of MedicineU.S. National Library of Medicine


Profiles in Science
   
Pinterest badge Follow Profiles in Science on Pinterest!

The Rosalind Franklin Papers

Title:
Letter from Rosalind Franklin to C. A. Knight pdf (70,277 Bytes) transcript of pdf
Letter from Rosalind Franklin to C. A. Knight
Description:
C. Arthur Knight was one of many virus researchers that Franklin visited during her 1954 trip to the United States. A colleague of Wendell Stanley, Robley Williams, and Heinz Fraenkel-Conrat, he sent her samples of cucumber virus and iodinated TMV. In this letter she reported that she had had trouble getting the samples to orient well enough to do x-ray diffraction with them.
Number of Image Pages:
1 (70,277 Bytes)
Date:
1954-12-17 (December 17, 1954)
Creator:
Franklin, Rosalind
Recipient:
Knight, C. A.
University of California, Berkeley
Source:
Original Repository: Churchill Archives Centre. The Papers of Rosalind Franklin
Rights:
Reproduced from the Franklin Collection at the Churchill Archives Centre with the permission of the copyright holder.
Subject:
Medical Subject Headings (MeSH):
Tobacco Mosaic Virus
X-Ray Diffraction
Exhibit Category:
Envisioning Viruses: Birkbeck College, London, 1953-1958
Folder Number:
2/35
Unique Identifier:
KRBBHC
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Series: Work on Tobacco Mosaic Virus (TMV)
Folder: Correspondence Relating to Franklin's First Visit to Berkeley, California, Mar. 1952 - Mar. 1958
Transcript:
17th December, 1954.
Dear Dr. Knight,
Thank you so much for your letter answering my long series of questions, and for the two virus specimens.
I have started to work with both materials, but have not yet succeeded in obtaining good enough orientation. They were almost dry on arrival, and I had some difficulty in re-wetting them. When I added a few drops of freshly boiled distilled water to the CV4 a white precipitate formed. However, there remains plenty of material free from this precipitate. Its mechanical properties seem rather different from those of TMV. It tends to stay as a gel at a greater dilution, which makes it more difficult to orientate. I think the I-TMV is going to be somewhat easier. Do you know how much iodine it contains?
I enclose a copy of a short paper which I am sending to "Nature". (If it is rejected as being too long for "Nature" I shall send it elsewhere). I should be grateful if you would be kind enough to show it to Professor Stanley and to Dr. Fraenkel-Conrat.
I will write again in a few weeks time to tell you whether I am having any success with your materials.
Best wishes for Christmas and the New Year,
Yours sincerely,
Rosalind Franklin.
Metadata Last Modified Date:
2009-12-11
Linked Data:
RDF/XML     JSON     JSON-LD     N3/Turtle     N-Triples