Original Repository: Oregon State University. Library. Ava Helen and Linus Pauling Papers
Reproduced with permission of the Ava Helen and Linus Pauling Papers. Oregon State University Library.
How Antibodies and Enzymes Work
March 20, 1940
Helen and I are glad to hear that your little boy is getting along well. We wish that we were closer to Manchester or that
Manchester were closer to Pasadena so that we could see him and you. Crellin has been developing not only physically but also
with respect to personality until now he has the most well developed and definite opinions in the family. Last night we had
Zechmeister at our house for a family dinner, and after we had touched wine glasses, Crellin insisted on touching his water
glass to all the wine glasses.
Zechmeister arrived about a week ago, bringing with him one assistant, Polgar. We expect that he will stay permanently. His
wife was in such poor health that she could not make the trip, but she will probably be able to come over during the summer.
We are glad to have Zechmeister here, and I am glad that you have good opinion of him.
I have been working recently on the development of a new and detailed theory of antibody structure and antibody formation.
Fortunately a Rockefeller Fellow, Dr. Dan Campbell, Assistant Professor of Immunology at Chicago, who had planned to spend
a year in Europe, came here instead, and he is now beginning some experimental tests of the theory. I was started on the immunology
problem two years ago by a two-day visit with Landsteiner, and I am going to see him Saturday night and talk with him about
the theory. I am leaving for New York in a couple of hours, to attend a meeting of the Guggenheim Board of Selection.
Our program of research in molecular structure is continuing to move along well. The electron diffraction technique is still
being profitably applied and the x-ray studies of simple substances related to proteins are giving good results, although
the work is hard and each structure determination takes a long time.
The only contribution which we have made to the political situation is in connection with the "Union Now" movement.
My wife and I are charter members of the local group and I have made a number of talks about it both here and in Oregon.