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The Harold Varmus Papers

Title:
Letter from Erling Norrby, Department of Virology, Karolinska Institute to Harold Varmus pdf (46,148 Bytes) transcript of pdf
Letter from Erling Norrby, Department of Virology, Karolinska Institute to Harold Varmus
Number of Image Pages:
1 (46,148 Bytes)
Date:
1987-07-28 (July 28, 1987)
Creator:
Norrby, Erling
Karolinska Institute. Department of Virology
Recipient:
Varmus, Harold
Source:
Original Repository: University of California, San Francisco. Archives and Special Collections. Harold E. Varmus Papers
Rights:
Reproduced with permission of Erling Norrby.
Subject:
Medical Subject Headings (MeSH):
Terminology as Topic
HIV
Acquired Immunodeficiency Syndrome
Retroviridae
Exhibit Category:
AIDS and HIV: Science, Politics, and Controversy, 1981-1993
Relation:
Metadata Record Letter from Harold Varmus to Erling Norrby, Department of Virology, Karolinska Institute (August 5, 1987) pdf (46,385 Bytes) transcript of pdf
/ps/access/MVBBLF.pdf
Box Number: 2
Folder Number: 13
Unique Identifier:
MVBBLD
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: UCSF Collections
SubSeries: Collection Number MSS 88-47
SubSubSeries: Human Retrovirus Study Group, 1981-1987
Folder: Human retrovirus study group correspondence, 1981-1987
Transcript:
July 28, 1987
Dear Harold,
You have the rather ungrateful responsibility of directing the discussions on terminology for human AIDS viruses.
As concerns immune deficiency virus (HIV) there is now evidence that this should be split into HIV type I and HIV type II. In fact the Montaigner group has already shifted their naming of virus strains from LAV-II to HIV-II. Apparently they have some problem in distinguishing naming of strains and designation of virus types. The basis for separation into two types is the fulfillment of the criterium of more than 50% difference in sequence homology between representative strains. In the case of comparison of LAV-I and LAV-II this was evidenced by the publication from Montaigner's group. Further Franscini et al. (In press Nature) in Gallo's laboratory has sequenced our virus isolate SBL 6669 which also shows about 43% homology with HIV-I strains.
For your information I send you some recent reprints and manuscripts which further emphasize the need to separate the two virus types.
I hope to see you some time in the near future.
Sincerely,
Erling Norrby
Metadata Last Modified Date:
2010-07-06
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