Mori, a former post-doctoral fellow in Sokoloff's lab, wrote to ask for further clarification on some equations for glucose
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1993-01-14 (January 14, 1993)
National Institute of Mental Health (U.S.)
Juntendo University School of Medicine
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Positron Emission Tomography Scanning and Beyond, 1979-2004
Letter from Kentaro Mori to Louis Sokoloff (December 13, 1992)
Letter from Louis Sokoloff to Kentaro Mori (November 10, 1992)
Letter from Kentaro Mori to Louis Sokoloff (October 26, 1992)
Box Number: 1
Folder Number: 52
January 14, 1993
Thanks for your letter of December 13, 1992. I have been slow in responding because I am trying to complete two huge chapters
for a textbook of Human Physiology, which were due at the end of 1992. I have not yet sent them out, but they are close to
In reference to your question about my statement "All units must be in molecular concentrations of methylglucose and glucose",
I mean that they should be in units of mmoles/liter or mM (or equivalents), in order to get your final answer for Vt and Kt
in molecular units. If you use only radioactive units, then your final units will relate only to the transport of radioactivity,
which is not really what you want. It is very simple for you to convert your counting rates or DPM into molecular units by
using the original specific activity of methylglucose. The supplier usually supplies you with information on uCi/umol or mCi/mmol.
If you divide uCi/ml by uCi/umole, you will come out with mol/ml. I hope this clarifies this issue for you. If not, do not
hesitate to ask.
We are all making our plans for the trip to Japan. When they are completed, we will let you know. At the present time it is
almost certain that my wife and son will accompany me and we will come to Tokyo for several days after the meeting in Sendai.