Mori, a former postdoctoral fellow in Sokoloff's lab, wrote to ask for further clarification on some equations for glucose
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1992-12-13 (December 13, 1992)
Juntendo University School of Medicine
Reproduced with permission of Kentaro Mori.
Positron Emission Tomography Scanning and Beyond, 1979-2004
Letter from Louis Sokoloff to Kentaro Mori (January 14, 1993)
Letter from Louis Sokoloff to Kentaro Mori (November 10, 1992)
Letter from Kentaro Mori to Louis Sokoloff (October 26, 1992)
Box Number: 1
Folder Number: 52
Dec. 13, 1992
Dear Dr. Sokoloff
How are you?
I think I spent must exciting time in September since I returned to Japan. I really enjoyed your clear lecture so much. I
would very much appreciated receiving a quick answer to my questions. Since I returned to Japan, I started to set up experimental
room to measure Vmax and KT. I bought a Beckman glucose analyzer (this is very expensive in Japan!) and microfuge. I set up
glucose clamp technique again. In my hospital it is prohibited to use radioisotope to experimental animals. I got permission
to sue a RI experimental room in pharmaceutical compnay. I will start RI experiment coming January! I want to show results
and want your comment when you come to Japan next year. I am very much exciting now.
By the way, I want to ask question again. According to your letter,
PSMG x Cp - MG = VT - MG - PSMG x KT - MG x (1 + Cp - glu/KT - glc)
You said "All units must be in molecular concentrations of methyl-glucose and glucose." However, I will be use radioactive
methylglucose in defferent plasma glucose concentration. So that I have only data of tracer concentration of methyglucose.
How can I manage Cp - MG in this equation? I am confusing. Would you answer to my question?
P.S. Recently I became assistant professor in my department because I learned a lot in your laboratory.