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The Louis Sokoloff Papers

Title:
Letter from Kentaro Mori to Louis Sokoloff pdf (69,316 Bytes) transcript of pdf
Letter from Kentaro Mori to Louis Sokoloff
Number of Image Pages:
2 (69,316 Bytes)
Date:
1992-10-26 (October 26, 1992)
Creator:
Mori, Kentaro
Juntendo University School of Medicine
Recipient:
Sokoloff, Louis
National Institute of Mental Health (U.S.)
Rights:
Reproduced with permission of Kentaro Mori.
Exhibit Category:
Positron Emission Tomography Scanning and Beyond, 1979-2004
Relation:
Metadata Record Letter from Louis Sokoloff to Kentaro Mori (January 14, 1993) pdf (57,063 Bytes) transcript of pdf
/ps/access/NLBBFH.pdf
Metadata Record Letter from Kentaro Mori to Louis Sokoloff (December 13, 1992) pdf (54,381 Bytes) transcript of pdf
/ps/access/NLBBFJ.pdf
Metadata Record Letter from Louis Sokoloff to Kentaro Mori (November 10, 1992) pdf (74,357 Bytes) transcript of pdf
/ps/access/NLBBFK.pdf
Box Number: 1
Folder Number: 52
Unique Identifier:
NLBBFL
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Transcript:
Oct. 26, 1992
Dear Dr. Sokoloff
I was very glad to see you again at NIH. I enjoyed your clear lectures very much. Since I returned to Japan, I have been looking for laboratory for Radio-isotope use because in my hospital we are prohibited from using RI for animals. But, I will love this problem soon.
I am always thinking about the equation to get Vm* and KT*. You gave me an equation to solve Vm* and KT* for methyl glucose as follows.
[EQUATIONS]
I have several question about equation.
Q1. To get Vm* and KT*. We need PS* values at different plasma glucose concentration. To get diffusion limitation of methyl glucose (m MG), we also need information about [lambda]MG and [lambda]IAP according to [Equation #1]. I know [lambda]MG is different at different plasma glucose concentration. How about [lambda]IAP? Is it different at different plasma glucose concentration? Do I need data of [lambda]IAP at different plasma glucose concentrations by different animal group?
Q2. [Equation #2] is final equation to get Vm* and KT*. I know KT for glucose is about 6.8. However, is KT same value at different plasma glucose concentration and different brain structures?
In pathological condition, I think KT should change. So, according to [Equation #3], it is impossible to get Vm* and KT* without information of KT. What do you think about that?
I know you are extremely busy person. But, could you answer my questions?
I am looking forward to seeing in Sendai next year. I will attend reunion party in Sendai.
Sincerely yours
Kentaro Mori
Metadata Last Modified Date:
2016-08-15
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