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The Louis Sokoloff Papers

[Autoradiograph of brain sections from rhesus monkeys showing effects of visual occlusion]
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This image accompanied one of the early publications demonstrating the DG method (Kennedy, et al., PNAS 73 (1976): 4230-4234) and was also used by Sokoloff to illustrate his Schmitt lecture in 1980. The caption reads, "Autoradiographs of coronal brain sections from rhesus monkeys at the level of the striate cortex. A: Animal with normal binocular vision. Note the laminar distribution of the density; the dark band corresponds to layer IV. B: Animal with bilateral visual deprivation. Note the almost uniform and reduced relative density, especially the virtual disappearance of the dark band corresponding to layer IV. C: Animal with right eye occluded. The half-brain on the left side of the photograph represents the left hemisphere contralateral to the occluded eye. Note the alternate dark and light striations, each approximately 0.3 to 0.4 mm in width, that represent the ocular dominance columns. These columns are most apparent in the dark band corresponding to layer IV, but extend through the entire thickness of the cortex. The arrows point to regions of bilateral asymmetry where the ocular dominance columns are absent. These are presumably areas with normally only monocular input. The one on the left, contralateral to occluded eye, has a continuous dark lamina corresponding to layer IV which is completely absent on the side ipsilateral to the occluded eye. These regions are believed to be the loci of the cortical representations of the blind spots."
Number of Image Pages:
1 (253,612 Bytes)
Date Supplied:
ca. 1975
[National Institute of Mental Health (U.S.)]
This item is in the public domain. It may be used without permission.
Medical Subject Headings (MeSH):
Exhibit Category:
Establishing the Foundation for PET Scanning: the 2-Deoxyglucose Method, 1968-1978
Box Number: 141
Folder Number: 11
Unique Identifier:
Document Type:
Slides (photographs)
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