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The Daniel Nathans Papers

Title:
Letter from David C. Ward to Daniel Nathans pdf (46,255 Bytes) transcript of pdf
Letter from David C. Ward to Daniel Nathans
Number of Image Pages:
1 (46,255 Bytes)
Date:
1971-01-13 (January 13, 1971)
Creator:
Ward, David C.
Imperial Cancer Research Fund Laboratories
Recipient:
Nathans, Daniel
Source:
Original Repository: Alan Mason Chesney Medical Archives. Daniel Nathans Collection
Rights:
Reproduced with permission of David C. Ward.
Subject:
Medical Subject Headings (MeSH):
Simian virus 40
DNA
Exhibit Category:
Restriction Enzymes and the "New Genetics," 1970-1980
Relation:
Metadata Record Letter from Daniel Nathans to David C. Ward (January 25, 1971) pdf (32,489 Bytes) transcript of pdf
/ps/access/PDBBDP.pdf
Unique Identifier:
PDBBDN
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Transcript:
13th January, 1971.
Dear Dr. Nathans,
Lionel Crawford and I have recently developed a procedure for strand separation of Form II SV40 DNA which utilizes synthetic polynucleotides as per Szybalski. We are planning to study single stranded viral DNA in a coupled in vitro protein synthesis system and would very much like to do experiments with a unique population of linear molecules. Your recent observations with B-restriction enzyme of E. coli suggests that it could provide such a population of DNA molecules. Would it be possible to obtain from you a sample of the B-enzyme for use in our system. Should you be able to spare a sample we will be happy to cover all transportation expenses.
Thanking you in advance.
Yours sincerely,
D. Ward.
Metadata Last Modified Date:
2009-12-01
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