Winge's reprints just arrived, and I've had the pleasure of reading them, I don't think you have much to quarrel
about with him, at least in the ultimate interpretations, although one may wonder whether you will agree with him in regard
to even the long-term adaptability of your mel- strains. Do you confirm his observations on galactose-fermentation by S.
Bayanus? When it comes down to it, in his G x gs crosses, he is demonstrating the transmission of the cytoplasmic mechanism
for long-term adaptation. Of course this is a "phenotypic" phenomenon -- so is your melibiose story. It seems to
me that it is this issue which differentiates your viewpoint from Lindegren's, since he has been talking about changes
of the locus, and you do not. In Winge's material, perhaps the most interesting experiment has not been done, namely
on the effect of preadaptation of the G parent on the rate of adaptation of the gs segregants of a G x gs cross, or even a
gs(adapted) x gs(nonadapted).
But the purpose of this letter is not to reconcile you with Winge, which it's none of my business to do, but to remind
you please to send me a copy of the first crude draft of the writeup of the pink yeast work, as soon as convenient.
When are you leaving St. Louis -- via the CSH meetings?