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The Sol Spiegelman Papers

Letter from Sol Spiegelman to Joshua Lederberg pdf (46,241 Bytes) transcript of pdf
Letter from Sol Spiegelman to Joshua Lederberg
Number of Image Pages:
1 (46,241 Bytes)
1948-03-04 (March 4, 1948)
Spiegelman, Sol
Lederberg, Joshua
This item is in the public domain. It may be used without permission.
Exhibit Category:
Enzymes and Genetics, 1940-1955
Metadata Record Letter from Joshua Lederberg to Sol Spiegelman (March 2, 1948) pdf (33,771 Bytes) transcript of pdf
Box Number: 6
Folder Number: 42
Unique Identifier:
Document Type:
Letters (correspondence)
Physical Condition:
Series: Correspondence, 1946-1983
Folder: Lederberg, Joshua, 1946-1978
March 4, 1948
Dear Josh:
Regarding your letter of March 2nd, it is about time you learned that in the observations of nature, when two apparently contradictory results are obtained, it is not always inevitably true that one must be right and one must be wrong. They both may be right or they both may be wrong.
Now with respect to the particular problem at hand, we found that it was necessary to dilute the dyes in the EMB plate to the point which permits growth. This point is different for different strains of yeast, and I am sorry that I am not in the position to give you the concentration that will permit MA and ma to develop. All of our work was done with the galactose fermenting system involving other strains. The general level we found was 2 cc. of a 2% eosine and 1/2 cc. of a .5% methylene blue per 100 cc. of media. For the more sensitive, of course, you would have to go below these concentrations.
Sincerely yours,
S. Spiegelman
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