In this article, Luria provided an overview of the state of knowledge of viruses and how they replicate. Though he accepted
Oswald Avery's proof that DNA was the "transforming principle" in bacteria, here he suggested that the protein
component of viruses, rather than DNA, might have the primary role in replication. Luria later explained to historian Horace
Judson that this oversight was primarily due to his "not thinking biochemically," adding that "I don't think
we attached great importance to whether the gene was protein or nucleic acid." Luria noted that James Watson and Francis
Crick's work on the structure of DNA in the early 1950s permanently settled the question.
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1950-05-12 (May 12, 1950)
Luria, Salvador E.
Periodical: Luria, Salvador E. "Bacteriophage: An Essay on Virus Reproduction." Science 111, 2889 (12 May 1950): 507-511. Article.
[American Association for the Advancement of Science]
Reprinted with permission from Luria, Salvador E. "Bacteriophage: An Essay on Virus Reproduction." Science 111, 2889
(12 May 1950): 507-511. Copyright 1950 AAAS.
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