Ultraviolet Irradiation of Bacteriophage during Intracellular Growth
In this paper, Luria and Latarjet described a subpopulation of E. coli, strain B infected with bacteriophage T2, with increased
resistance to UV. They indicated that the infected bacteria initially showed a rapid increase in resistance due to increased
resistance of the intracellular phage particles, possibly caused by accumulation of ultraviolet-absorbing material around
the phage. With time, the resistance of infected bacteria to high doses of radiation decreases, likely indicating that, as
phage multiplication proceeds, the apparent sensitivity of the intracellular phage particles returns to higher values. Luria
spent the 1945-1946 academic year on leave in Cold Spring Harbor, directing a government research project on bacterial resistance
to antibiotics. The research produced several papers, including this one.
Item is a photocopy.
Number of Image Pages:
15 (1,520,663 Bytes)
1947-02 (February 1947)
Luria, Salvador E.
Latarjet, Raymond L.
Periodical: Luria, Salvador E., and Raymond L. Latarjet. "Ultraviolet Irradiation of Bacteriophage during Intracellular Growth."
Journal of Bacteriology 53, 2 (February 1947): 149-163. Article. 15 Images.
[American Society for Microbiology]
Reproduced with permission of the American Society for Microbiology.
Reproduced with permission of the American Philosophical Society.