Letter from Rudolph J. Anderson to Florence R. Sabin
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1929-10-05 (October 5, 1929)
Anderson, Rudolph J.
Sabin, Florence R.
Original Repository: American Philosophical Society. Library. Florence R. Sabin Papers
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At the Rockefeller Institute for Medical Research, 1925-1938
Letter from Florence R. Sabin to Rudolph J. Anderson (October 4, 1929)
Anderson, Rudolph J., #11
Dear Doctor Sabin,
Many thanks for the information contained in your letter of the 4th. I had been hoping that you would find some similarity
in behavior between the liquid saturated fatty acid of the avian phosphatide and the less optically active fraction of the
acids from the acetone-soluble fat. The logical thing would be to find the greatest biological effect from the optically active
The acid from the avian phosphatide showed no optical activity although it may contain a small fraction of an optically active
acid. Hence I would have been surprised if you had found that it was just as active biologically as phthioic acid [human phosphatide
The correlation of biological activity with optical activity is very interesting but we must not let our hopes and theories
influence our judgment.
I shall be glad to learn of your finding in regard to the bovine phosphatide.