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The Francis Crick Papers

Title:
Interim Note: Studies on the Physical Properties of the Cytoplasm of Cells in Tissue Culture pdf (323,164 Bytes) transcript of pdf
Interim Note: Studies on the Physical Properties of the Cytoplasm of Cells in Tissue Culture
Description:
The technique to which Crick referred here was invented by Arthur Hughes, a technique by which small particles of magnetic ore were inserted into cultured chick fibroblast cells. The cells engulfed the particles, which could then be moved around inside the cells by an applied magnet field, yielding data on the physical properties of the cytoplasm, the material of the cell that surrounds the nucleus. Crick described and analyzed the results obtained from these experiments in two papers, mentioned here as drafts and published in 1950, his first published papers.
More importantly for his scientific career in the long term, Crick in this note declared his intention to transfer to the Medical Research Council's unit at the Cavendish Laboratory in order to study the structure of proteins with Max Perutz.
Number of Image Pages:
3 (323,164 Bytes)
Date Supplied:
March 1949
Creator:
Crick, Francis
Source:
Original Repository: Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
URL: http://archives.wellcome.ac.uk/Exit
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Rights:
Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine.
URL: http://library.wellcome.ac.uk/Exit
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Subject:
Medical Subject Headings (MeSH):
Cytoplasm
Exhibit Category:
Biographical Information
Relation:
Metadata Record The Physical Properties of Cytoplasm: A Study by Means of the Magnetic Particle Method, Part I. Experimental (1950) pdf (3,910,164 Bytes) ocr (101,973 Bytes)
/ps/access/SCBBYR.pdf
Metadata Record The Physical Properties of Cytoplasm: A Study by Means of the Magnetic Particle Method, Part II. Theoretical Treatment (1950) pdf (1,656,600 Bytes) ocr (51,773 Bytes)
/ps/access/SCBBYS.pdf
Box Number: 2
Folder Number: PP/CRI/A/2/1
Unique Identifier:
SCBBBB
Document Type:
Reports
Laboratory notes
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Personal Material
SubSeries: Correspondence
Folder: MRC: Studentship and Employment
Transcript:
20th May, 1974
Dear Tom,
Thank you for your kind words about my article and especially for your reminiscences. It is really rather surprising how Chargaff, while frequently being witty, has almost always been wrong. Pirie, though rather different in character, has always been obstinately sceptical. I had no idea that he said that about the genetic code in 1963 and would be glad to have the reference.
As you probably know, I first realised that nucleic acid would have a lot of evolutionary information in 1958. I have always been mildly supprised that I subsequently have done nothing about it but thanks to your efforts and those of several others the matter seems to be in good hands.
I have given up travelling for the time being so that I can lead a quiet life, so we are unlikely to meet in the near future unless you come to England.
Best wishes,
F.H.C. Crick
Metadata Last Modified Date:
2010-12-13
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