In this letter Crick referred to work in Khorana's laboratory on alanine tRNA in yeast and in the bacterium E-coli, as
well as on the TAG codon in DNA, which becomes UAG during transcription into RNA and which codes for the termination of a
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1969-04-16 (April 16, 1969)
Khorana, H. Gobind
Original Repository: Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
I was sorry to hear that you had not been feeling quite your usual self. If you want to come to Cambridge, either on your
way to Switzerland or on the way back, you are always welcome. There is no need to feel that you have to do any work while
you are here. We can just relax by the Cam.
I quite agree, it is sensible not to worry too much at this stage about the sequence of the alanine tRNA. However, I feel
somebody ought to check it. I am not sure whether the people here on the top floor would be interested in doing this.
If you could send us informational amounts of the TAG polymer, we would really be extremely grateful. Malcolm Gefter tells
me that he can easily tool up to multiply and transcribe it.
I am not coming to the Gordon Conference this year, but Brian Clark and John Finch hope to be there. Just another reason
for you to drop in to see us here.