I have just had a letter from Danny Lehrman reminding us that we said we would visit his laboratory when we are both over
there in October. I am still keen to do this. Are you? If so I think we should try to arrange a time otherwise it may turn
out that the two of us cannot go on the same day. The obvious days are either Tuesday 17th October or Saturday 2lst October.
As far as I am concerned the latter would be preferable providing Saturday is a possible day for Lehrman. Let me know what
you feel. I expect Sydney will also come, but as he is in the States at the moment I cannot ask him which day is better for
There has been no change in our plans for Greece this year. We expect to go out about the middle of June and stay there till
the end of July, although I have heard very little from the man who is looking after the boat and the engines. I think the
most sensible idea would be to try to meet at a port in the middle of the Aegean soon after you have left Spetsai. It might
be sensible if we fixed on a particular port and the approximate date, although I think we should have some other means of
keeping in touch in case we miss each other. Which port do you think would be best for our rendezvous? I seem to remember
you suggested Ios.
Sydney and the others have some suggestive evidence that UGA produces polypeptide chain termination. In brief, they have
a strong suppressor which is specific for UGA and using this have converted two ochre mutants in B-galactosidase into UGA
and shown that they have the same polar properties as do the ochre and amber at the same sites. Zipser has done something
similar. However, we still lack direct evidence that UGA chain terminates, and because it is suppressed so easily we still
think that UAA is the triplet commonly used for chain termination.
I have made some progress on the problem of why proteins aggregate using dyads. It is more complicated than I expected, but
at least I can see the reasons in a general way. Probably the best time to talk about this would be when we meet in the summer.